CD36

CD36 (diferenciační skupina 36) je lidský glykoprotein, který je kódován genem Cd36. Je tvořen 15 exony rozprostírajících se v pásmu q11.2 chromozomu 7 a zabírá nejméně 32 kbp této oblasti.^[1] Je známý také jako glykoprotein destiček 4, translokáza mastných kyselin či jako scavenger receptor 3 třídy B (SCARB3). Jako transmembránový glykoproteinový receptor se nachází u obratlovců na povrchu mnoha buněčných typů a váže velké množství ligandů včetně kolagenu,^[2] trombospondinu,^[3] erytrocytů infikovaných parazitem Plasmodium falciparum,^[4] oxidovaných nízkodenzitních lipoproteinů (ox-LDL)^[5] i nativních lipoproteinů^[6] či oxidovaných fosfolipidů^[7]. Váže také mastné kyseliny s dlouhým řetězcem^[8] a je důležitý pro jejich import do buňky.^[9]

↑ ARMESILLA, A. L.; VEGA, M. A. Structural organization of the gene for human CD36 glycoprotein. The Journal of Biological Chemistry. 1994-07-22, roč. 269, čís. 29, s. 18985–18991. PMID 7518447. Dostupné online [cit. 2021-02-04]. ISSN 0021-9258. PMID 7518447.
↑ Tandon NN, Kralisz U, Jamieson GA. Identification of glycoprotein IV (CD36) as a primary receptor for platelet-collagen adhesion. The Journal of Biological Chemistry. May 1989, s. 7576–83. Dostupné online. PMID 2468670. ^{[nedostupný zdroj]}
↑ Silverstein RL, Baird M, Lo SK, Yesner LM. Sense and antisense cDNA transfection of CD36 (glycoprotein IV) in melanoma cells. Role of CD36 as a thrombospondin receptor. The Journal of Biological Chemistry. August 1992, s. 16607–12. Dostupné online. PMID 1379600. ^{[nedostupný zdroj]}
↑ Oquendo P, Hundt E, Lawler J, Seed B. CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Cell. July 1989, s. 95–101. DOI 10.1016/0092-8674(89)90406-6. PMID 2473841. S2CID 22059108.
↑ Nicholson AC, Frieda S, Pearce A, Silverstein RL. Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site. Arteriosclerosis, Thrombosis, and Vascular Biology. February 1995, s. 269–75. Dostupné v archivu pořízeném dne 2013-02-23. DOI 10.1161/01.ATV.15.2.269. PMID 7538425.
↑ Calvo D, Gómez-Coronado D, Suárez Y, Lasunción MA, Vega MA. Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL. Journal of Lipid Research. April 1998, s. 777–88. Dostupné online. PMID 9555943. ^{[nedostupný zdroj]}
↑ Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, Sun M, Finton PJ, Shan L, Gugiu B, Fox PL, Hoff HF, Salomon RG, Hazen SL. Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. The Journal of Biological Chemistry. October 2002, s. 38503–16. DOI 10.1074/jbc.M203318200. PMID 12105195.
↑ Baillie AG, Coburn CT, Abumrad NA. Reversible binding of long-chain fatty acids to purified FAT, the adipose CD36 homolog. The Journal of Membrane Biology. September 1996, s. 75–81. DOI 10.1007/s002329900111. PMID 8694909. S2CID 5911289.
↑ POHL, Jürgen; RING, Axel; KORKMAZ, Umine. FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts. Molecular Biology of the Cell. 2005-01, roč. 16, čís. 1, s. 24–31. PMID 15496455 PMCID: PMC539148. Dostupné online [cit. 2021-02-04]. ISSN 1059-1524. DOI 10.1091/mbc.e04-07-0616. PMID 15496455.

[1] ARMESILLA, A. L.; VEGA, M. A. Structural organization of the gene for human CD36 glycoprotein. The Journal of Biological Chemistry. 1994-07-22, roč. 269, čís. 29, s. 18985–18991. PMID 7518447. Dostupné online [cit. 2021-02-04]. ISSN 0021-9258. PMID 7518447.

[pmid2468670-2] Tandon NN, Kralisz U, Jamieson GA. Identification of glycoprotein IV (CD36) as a primary receptor for platelet-collagen adhesion. The Journal of Biological Chemistry. May 1989, s. 7576–83. Dostupné online. PMID 2468670. ^{[nedostupný zdroj]}

[pmid1379600-3] Silverstein RL, Baird M, Lo SK, Yesner LM. Sense and antisense cDNA transfection of CD36 (glycoprotein IV) in melanoma cells. Role of CD36 as a thrombospondin receptor. The Journal of Biological Chemistry. August 1992, s. 16607–12. Dostupné online. PMID 1379600. ^{[nedostupný zdroj]}

[pmid2473841-4] Oquendo P, Hundt E, Lawler J, Seed B. CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Cell. July 1989, s. 95–101. DOI 10.1016/0092-8674(89)90406-6. PMID 2473841. S2CID 22059108.

[pmid7538425-5] Nicholson AC, Frieda S, Pearce A, Silverstein RL. Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site. Arteriosclerosis, Thrombosis, and Vascular Biology. February 1995, s. 269–75. Dostupné v archivu pořízeném dne 2013-02-23. DOI 10.1161/01.ATV.15.2.269. PMID 7538425.

[pmid9555943-6] Calvo D, Gómez-Coronado D, Suárez Y, Lasunción MA, Vega MA. Human CD36 is a high affinity receptor for the native lipoproteins HDL, LDL, and VLDL. Journal of Lipid Research. April 1998, s. 777–88. Dostupné online. PMID 9555943. ^{[nedostupný zdroj]}

[pmid12105195-7] Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, Sun M, Finton PJ, Shan L, Gugiu B, Fox PL, Hoff HF, Salomon RG, Hazen SL. Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36. The Journal of Biological Chemistry. October 2002, s. 38503–16. DOI 10.1074/jbc.M203318200. PMID 12105195.

[pmid8694909-8] Baillie AG, Coburn CT, Abumrad NA. Reversible binding of long-chain fatty acids to purified FAT, the adipose CD36 homolog. The Journal of Membrane Biology. September 1996, s. 75–81. DOI 10.1007/s002329900111. PMID 8694909. S2CID 5911289.

[9] POHL, Jürgen; RING, Axel; KORKMAZ, Umine. FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts. Molecular Biology of the Cell. 2005-01, roč. 16, čís. 1, s. 24–31. PMID 15496455 PMCID: PMC539148. Dostupné online [cit. 2021-02-04]. ISSN 1059-1524. DOI 10.1091/mbc.e04-07-0616. PMID 15496455.

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